Case recruitment in genetic association studies: larger sample size or greater homogeneity?
نویسندگان
چکیده
711 Graduate Institute of Epidemiology, College of Public Health, National Taiwan University, No. 1, Jen-Ai Road, 1st Section, Taipei, Taiwan. E-mail: [email protected] In the previous example of cardiovascular diseases, suppose that the researcher has at his/her disposal, 300 patients with myocardial infarction (n1 = 300), 300 patients with stroke (n2 = 300), and 600 control subjects (n0 = 600). A literature search revealed that the allele frequencies are p1 = 0.158, p2 = 0.149, and p0 = 0.095, respectively. 1 Since
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عنوان ژورنال:
- International journal of epidemiology
دوره 34 3 شماره
صفحات -
تاریخ انتشار 2005